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Saturday, 10 June, 2006

Infrared Spectroscopic Mapping of Single Nanoparticles and Viruses at Nanoscale Resolution

M. Brehm, T. Taubner, R. Hillenbrand, and F. Keilmann -
Nano Letters 6, 1307-1310 (2006)

We demonstrate that scattering near-field microscopy (s-SNOM) can determine infrared "fingerprint" spectra of individual poly(methyl methacrylate) nanobeads and viruses as small as 18 nm. Amplitude and phase spectra are found surprisingly strong, even at a probed volume of only 10-20 l, and robust in regard to particle size and substrate. This makes infrared spectroscopic s-SNOM a versatile tool for chemical and-in the case of protein-secondary-structure identification.

Article on the journal's website