Thursday, 15 May, 2014
DNA Origami Structures Directly Assembled from Intact Bacteriophages
P. Nickels, Y. Ke, R. Jungmann, D. Smith, M. Leichsenring, W. Shih, T. Liedl, and B. Högberg -
Small, Vol. 10 (9), pp 1765–1769 (2014)
Keeping it simple: a purified DNA single strand derived from bacteriophage M13 is typically used as scaffold material for DNA origami. This requires time-consuming purification procedures to attain single-stranded DNA. The direct use of intact bacteriophage particles as a scaffold source for DNA origami assemblies is reported.