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Monday, 17 November, 2014

From Genes to Protein Mechanics on a Chip

Mechanical forces play a pivotal role in biological systems by performing tasks such as guiding cell adhesion, inducing gene expression patterns and directing stem cell differentiation. At the molecular level, mechano-sensitive proteins act as sensors and transducers, communicating the presence and direction of applied forces to downstream signaling cascades. With the rapid development of single molecule techniques, the underlying chanisms have now become accessible.

 

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Publication "From genes to protein mechanics on a chip"