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Monday, 23 August, 2010

New approach for cancer medication discovered

TUM researchers demonstrate rocking movement in the anti-stress protein Hsp90


© C. Ratzke et al.

The protein Hsp90 plays a significant role in the survival of cells that are exposed to stress. Researchers at the Technische Universität München (TUM) uncovered this proteins mode of operation some time ago but now Hsp90 has surprised even the experts with an unexpected pattern of motion. The results are published in the current online issue of the renowned science journal PNAS and may help researchers discover specific cancer medication.


Presseinformation der TUM (deutsch)
Press information TUM (english)
Publication "Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle"