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CeNS Center for NanoScience LMU Ludwig-Maximilians-Universität München
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Daniel Schiffels

German

Curriculum Vitae

Since 2010

PhD student in the group of Prof. Tim Liedl, LMU Munich

2009 – 2010

Diploma Thesis, University of California Santa Barbara

2006 - 2007

Erasmus year, Universidad de Sevilla, Spain

2006

Vordiplom

2004 - 2010

Diploma in Physics at the LMU Munich

 

Scholarships

Since 2010

Scholarship of the IDK-NBT (Elite Network of Bavaria)

2006 - 2007

Erasmus Stipend

Research Project

Functionalization of DNA origami structures

We are interested in engineering functional DNA devices using the DNA origami method. Those devices will enable a powerful new approach to the development of tools for cellular and molecular biology studies. 

In particular we are interested in a better mechanical understanding of the transport of objects from the exterior of the cell to the endosome or the cytosol which is likely to accelerate development of concerted drug delivery techniques.

We are therefore working on vesicle encapsulated mechanotransducers that can be targeted to the endocytic pathway and report on the mechanical stresses throughout. For optimum optical readout we use fluorescent DNA-silver clusters that can be precisely positioned on DNA origami structures.