Carlo Bäjen
German

Curriculum Vitae
Since 2010 | PhD student in the group of |
2010 - 2011 | Patent engineer (Pat.-Ing.): |
2010 | Foreign research master student, |
2008 - 2010 | Master of Science in Engineering: |
2004 – 2008 | Diplom-Ingenieur (FH): |
Topic of Diploma Thesis: ”Genetic basis for degrading of methyl-tert.-butylether by Aquincola tertiaricarbonis |
Scholarships
since 2011 | Scholarship of the IDK-NBT (Elite Network of Bavaria) |
since 2011 | e-fellows.net fellowship |
2010 | Exchange scholarship, Austrian Marshall Plan Foundation, Vienna, Austria (Semester abroad at Rockefeller University) |
Research Project
"I am mainly interested in gene transcription and regulation in yeast, specifically focusing on interactions between (i) transcription factors (TFs), (ii) splicing factors, and (iii) further regulatory complexes (i.e. Ccr4-Not), which contain RNA recognition domains, and the nascent mRNAs. For that reason I am establishing cutting-edge assays, such as photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (referred to as PAR-CLIP; Hafner et al., 2010), ChIP Exo (Pugh, 2011), and RNA-Sequencing using next-generation sequencing (NGS) technologies, to obtain TF-binding motifs and all information we are interested in. Resulting data will be compared and correlated to existing data sets generated through ChIP-chip experiments, genome-wide occupancy profiles (Mayer et al., 2010), and dynamic transcriptome analysis (DTA); a new non-perturbing metabolic RNA labeling assay (Miller et al., 2010). These studies are expected to reveal significant insights into further complex interactions in biological systems."

