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PhD Position – Probing the Structure, Interactions, and Processing of Nucleic Acids with Single-Molecule Magnetic Tweezers

A position in the field of single-molecule biophysics will be available in 2014.

Project: The research focus is on using novel torque measuring magnetic tweezers to unravel the structure of DNA and RNA and to dissect nucleic acid-protein interactions at the single-molecule level. Specific questions concern the structural transitions of nucleic acids under forces and torques, the process of integration of viral genomic information into the host’s DNA, and on RNA and DNA processing enzymes. In addition to magnetic tweezers, the project with draw on additional single molecule methods such as atomic force microscopy and fluorescence, conventional bulk assays, and computer based molecular modeling.

Requirements: The applicant should hold a master’s degree (or equivalent) in physics, chemistry, molecular biology, or a similar discipline, have a proven track record of academic excellence, and be highly motivated to work in an international and interdisciplinary team.

Group: Prof. Jan Lipfert, Department of Physics, LMU Munich

Prof. Lipfert's website